Hematocytological, biochemical, and hemostasis parameters’ role in predicting the possibility of the various forms of the COVID-19 course in hospitalized Ukrainian patients: A cross-sectional study.

Publication date: Jul 01, 2023

The main objective of this study is to establish the characteristics of blood laboratory parameters in hospitalized coronavirus disease 2019 (COVID-19) Ukrainian patients and the significance of the above-mentioned parameters for predicting the course of the disease. Hematocytological, biochemical, and hemostasis methods of research have been used. Groups of patients with different forms of the coronavirus disease course have been analyzed (lethality – recovery, recovery with a severe and mild course). Age is one of the risk factors for COVID-19 mortality. Absolute values of neutrophils, neutrophil-lymphocyte ratio (NLR), systemic inflammation index, d-dimer, C-reactive protein, and soluble fibrin complex can be used by clinicians to effectively differentiate between two possible outcomes (lethality vs. recovery). A higher number of stab leukocytes, d-NLR, and platelets concentration have been recorded in patients with severe COVID-19 cases, compared to mild ones. The risk of adverse COVID-19 outcome (lethality) is significantly linked with d-dimer and NLR (odds ratio 1. 42). The risk of a severe course of the disease was significantly associated with the count of leukocytes (odds ratio 4. 96).

Concepts Keywords
Coronavirus biochemical parameters
Hematocytological COVID‐19
Laboratory hematocytological parameters
Platelets hemostasis parameters
Ukrainian laboratory diagnostics


Type Source Name
pathway REACTOME Hemostasis
disease MESH COVID-19
disease IDO blood
disease VO age
disease MESH inflammation

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