Publication date: Jul 09, 2023
“”The arrows go both ways,” he says. There’s also been some compelling if preliminary research showing the link between specific gut bacteria and serious mental illness. If we start to see signals between specific gut bacteria and specific behaviors or symptoms, then that can provide evidence for a microbial pathway that influences autism presentation. And of course, they have a number of functions in the gut, like regulating gut motility and the permeability of the intestinal barrier. Last February, what might be the first case report of fecal transplants in major depression in humans showed that fecal transplants successfully alleviated symptoms in two people. More research is underway. For Holingue, the connection between the gut and mental health is both scientific and personal. And that didn’t make sense, since the onset of GI symptoms was relatively new and I had been dealing with mental health struggles my whole life. “And I wondered if maybe there was a link between my mental health and the GI symptoms I was experiencing,” she recalls now. Her doctors shrugged off her questions.
| Concepts | Keywords |
|---|---|
| Diarrhea | Autism |
| Fungi | Brain |
| Npr | Conditions |
| Psychologist | Connection |
| Disorder | |
| Fecal | |
| Gut | |
| Link | |
| Mental | |
| Microbes | |
| Microbiome | |
| Nervous | |
| Symptoms | |
| System | |
| Transplants |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Autism |
| drug | DRUGBANK | Nonoxynol-9 |
| disease | MESH | obsessive-compulsive disorder |
| disease | MESH | schizophrenia |
| disease | MESH | depression bipolar |
| disease | MESH | mental illness |
| drug | DRUGBANK | Tropicamide |
| pathway | REACTOME | Vitamins |
| drug | DRUGBANK | Serotonin |
| disease | MESH | major depressive disorder |
| disease | MESH | ADHD |
| disease | MESH | neurodevelopmental disorders |
| disease | MESH | irritable bowel syndrome |