The evolution of Big Data in neuroscience and neurology

The evolution of Big Data in neuroscience and neurology

Publication date: Jul 10, 2023

Neurological diseases are on the rise worldwide, leading to increased healthcare costs and diminished quality of life in patients. In recent years, Big Data has started to transform the fields of Neuroscience and Neurology. Scientists and clinicians are collaborating in global alliances, combining diverse datasets on a massive scale, and solving complex computational problems that demand the utilization of increasingly powerful computational resources. This Big Data revolution is opening new avenues for developing innovative treatments for neurological diseases. Our paper surveys Big Data’s impact on neurological patient care, as exemplified through work done in a comprehensive selection of areas, including Connectomics, Alzheimer’s Disease, Stroke, Depression, Parkinson’s Disease, Pain, and Addiction (e. g., Opioid Use Disorder). We present an overview of research and the methodologies utilizing Big Data in each area, as well as their current limitations and technical challenges. Despite the potential benefits, the full potential of Big Data in these fields currently remains unrealized. We close with recommendations for future research aimed at optimizing the use of Big Data in Neuroscience and Neurology for improved patient outcomes.

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Concepts Keywords
Healthcare Big
Neuroscience Computational
Opioid Costs
Parkinsons Disease
Worldwide Diseases


Type Source Name
disease MESH Stroke
disease MESH Opioid Use Disorder
drug DRUGBANK Ilex paraguariensis leaf
drug DRUGBANK Nonoxynol-9
drug DRUGBANK Coenzyme M
disease MESH neurological disorders
disease MESH multiple sclerosis
disease MESH death
drug DRUGBANK Isoxaflutole
drug DRUGBANK Sulpiride
disease MESH brain diseases
disease MESH lifestyle
drug DRUGBANK L-Valine
drug DRUGBANK Huperzine B
disease MESH Mild Cognitive Impairment
disease MESH abnormalities
disease MESH major depressive disorder
disease MESH bipolar disorder
disease MESH aids
disease MESH neurodegenerative diseases
disease MESH autism
disease MESH schizophrenia
disease MESH dementia
drug DRUGBANK Flunarizine
drug DRUGBANK Tilmicosin
drug DRUGBANK Sertraline
disease MESH migraine
disease MESH epilepsy
drug DRUGBANK Gold
disease MESH tumor
drug DRUGBANK Ranitidine
disease MESH Attention Deficit Hyperactivity Disorder
disease MESH inflammation
disease MESH pathogenesis
drug DRUGBANK Dopamine
drug DRUGBANK Levodopa
disease MESH substance abuse
drug DRUGBANK Nicotine
drug DRUGBANK Ethanol
drug DRUGBANK Diamorphine
disease MESH Chronic pain
disease MESH syndromes
disease MESH Carpal Tunnel Syndrome
disease MESH peripheral neuropathy
disease MESH Lower Back Pain
drug DRUGBANK Trestolone
disease MESH bleeding
disease MESH infection
drug DRUGBANK Metamfetamine
drug DRUGBANK Cocaine
drug DRUGBANK Methadone
drug DRUGBANK Medical Cannabis
disease MESH suicide
disease MESH Alcohol Dependence
disease MESH genetic markers
disease MESH paresthesia
disease MESH gait
disease MESH complications
drug DRUGBANK Tretinoin
disease MESH osteoarthritis
disease MESH interstitial cystitis
disease MESH motor disorders
drug DRUGBANK Acetohydroxamic acid
disease MESH movement disorder
disease MESH neuropathic pain
drug DRUGBANK Indoleacetic acid
disease MESH Back Pain
disease MESH Fibromyalgia
disease MESH Irritable Bowel Syndrome
disease MESH Vulvodynia
disease MESH Cerebral Palsy
disease MESH Spinal Muscular Atrophy
disease MESH Autism Spectrum Disorder
disease MESH Kidney Diseases
disease MESH Arthritis
disease MESH Skin Diseases
drug DRUGBANK Calcium
disease MESH Hysteria
drug DRUGBANK Guanosine
disease MESH psychosis
drug DRUGBANK Adenosine
disease MESH headache disorders
disease MESH hemorrhagic stroke
disease MESH brain infarcts
disease MESH Hyperhomocysteinemia
disease MESH intracranial aneurysm
disease MESH Epileptic seizure
drug DRUGBANK Pentaerythritol tetranitrate
disease MESH inflammatory bowel disease
disease MESH parkinson disease
disease MESH vascular dementia
drug DRUGBANK Cinacalcet
drug DRUGBANK Trihexyphenidyl
drug DRUGBANK Profenamine
disease MESH Parkinsonism
disease MESH psychiatric disorders
drug DRUGBANK Carboxyamidotriazole
disease MESH central sensitization
disease MESH spondylolisthesis
disease MESH knee osteoarthritis
disease MESH hip osteoarthritis
disease MESH delusion
disease MESH illusion
disease MESH COVID 19
drug DRUGBANK Esomeprazole
disease MESH impulsivity
disease MESH Postoperative PAIN
disease MESH spinal diseases
disease MESH Chronic spontaneous urticaria

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