Correlation of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) with radiographic features of congestion in chest CT scan of patients with COVID-19.

Publication date: Jul 13, 2023

Given the importance of chest computed tomography (CT) to differentiate congestion from COVID-19 pneumonia, and considering the association of chest CT findings with cardiac biomarkers in patients with concomitant COVID-19 and heart failure, this study was conducted to identify the correlation between plasma NT-proBNP level and radiographic features of congestion in patients with COVID-19. This retrospective cohort research was carried out on adult hospitalized patients with COVID-19 and the plasma concentration of NT-proBNP was measured. The most important findings in chest CT have been considered to differentiate COVID-19 pneumonia from congestion. The study population was divided into two groups based on the presence of these imaging characteristics. Totally, 180 patients with a mean age of 59. 6 +/- 14. 6 years were included in the research. The radiographic findings related to congestion have been found in chest CT of 107 (59. 4%) patients. Mean plasma concentration of NT-proBNP in patients with and without radiographic features of congestion was 9886. 5 +/- 12,676 and 2079. 9 +/- 4209. 3 pg/mL, respectively (p 

Concepts Keywords
Biomarkers Biomarkers
Cardiac Congestion
Pneumonia Coronavirus infections
Pro NT-proBNP


Type Source Name
disease MESH COVID-19
disease MESH pneumonia
disease MESH heart failure
disease VO population
disease MESH Coronavirus infections

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