A comparison of the biomechanical properties of three different lumbar internal fixation methods in the treatment of lumbosacral spinal tuberculosis: finite element analysis.

Publication date: Jul 13, 2023

There are various internal fixation methods in treating lumbosacral spinal tuberculosis. The study compared the stability and stress distribution in surrounding tissues/implants, such as discs, endplates and screw-rod internal fixation system, etc. when applying three different lumbar internal fixation methods to treat lumbosacral spinal tuberculosis. A finite element model was constructed and validated. The spinal stability was restored using three methods: a titanium cage with lateral double screw-rod fixation (group 1), autologous bone with posterior double screw-rod fixation (group 2), and a titanium cage with posterior double screw-rod fixation (group 3). For comparison, group 4 represented the intact L3-S1 spine. Finally, a load was applied, and the ranges of motion and Von Mises stresses in the cortical endplates, screw-rod internal fixation system and cortical bone around the screws in the different groups were recorded and analyzed. All six ranges of motion (flexion, extension, left/right lateral bending, left/right rotation) of the surgical segment were substantially lower in groups 1 (0. 53^0 ~ 1. 41^0), 2 (0. 68^0 ~ 1. 54^0) and 3 (0. 55^0 ~ 0. 64^0) than in group 4 (4. 48^0 ~ 10. 12^0). The maximum stress in the screw-rod internal fixation system was clearly higher in group 2 than in groups 1 and 3 under flexion, left/right lateral bending, and left/right rotation. However, in extension, group 1 had the highest maximum stress in the screw-rod internal fixation system. Group 2 had the lowest peak stresses in the cortical endplates in all directions. The peak stresses in the cortical bone around the screws were higher in group 1 and group 2 than in group 3 in all directions. Thus, titanium cage with posterior double screw-rod fixation has more advantages in immediate reconstruction of lumbosacral spinal stability and prevention of screw loosening.

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Concepts Keywords
Biomechanical Cortical
Surgical Double
Titanium Fixation
Tuberculosis Group
Internal
Left
Lumbosacral
Right
Rod
Screw
Spinal
Stability
Stress
System
Tuberculosis

Semantics

Type Source Name
disease MESH spinal tuberculosis
drug DRUGBANK Titanium
drug DRUGBANK Coenzyme M
disease MESH osteoarticular tuberculosis
disease MESH kyphosis
drug DRUGBANK Isoniazid
drug DRUGBANK Rifampicin
drug DRUGBANK Ethambutol
drug DRUGBANK Pyrazinamide
disease MESH tuberculosis
pathway KEGG Tuberculosis
disease MESH complications
drug DRUGBANK Medroxyprogesterone acetate
disease MESH abscesses
disease MESH prosthesis loosening
disease MESH spinal diseases
disease MESH defects
disease MESH lordosis
disease MESH deformity
drug DRUGBANK Guanosine
drug DRUGBANK Sulodexide
disease MESH spondylitis
pathway REACTOME Reproduction

Original Article

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