Publication date: Jul 13, 2023
There are various internal fixation methods in treating lumbosacral spinal tuberculosis. The study compared the stability and stress distribution in surrounding tissues/implants, such as discs, endplates and screw-rod internal fixation system, etc. when applying three different lumbar internal fixation methods to treat lumbosacral spinal tuberculosis. A finite element model was constructed and validated. The spinal stability was restored using three methods: a titanium cage with lateral double screw-rod fixation (group 1), autologous bone with posterior double screw-rod fixation (group 2), and a titanium cage with posterior double screw-rod fixation (group 3). For comparison, group 4 represented the intact L3-S1 spine. Finally, a load was applied, and the ranges of motion and Von Mises stresses in the cortical endplates, screw-rod internal fixation system and cortical bone around the screws in the different groups were recorded and analyzed. All six ranges of motion (flexion, extension, left/right lateral bending, left/right rotation) of the surgical segment were substantially lower in groups 1 (0. 53^0 ~ 1. 41^0), 2 (0. 68^0 ~ 1. 54^0) and 3 (0. 55^0 ~ 0. 64^0) than in group 4 (4. 48^0 ~ 10. 12^0). The maximum stress in the screw-rod internal fixation system was clearly higher in group 2 than in groups 1 and 3 under flexion, left/right lateral bending, and left/right rotation. However, in extension, group 1 had the highest maximum stress in the screw-rod internal fixation system. Group 2 had the lowest peak stresses in the cortical endplates in all directions. The peak stresses in the cortical bone around the screws were higher in group 1 and group 2 than in group 3 in all directions. Thus, titanium cage with posterior double screw-rod fixation has more advantages in immediate reconstruction of lumbosacral spinal stability and prevention of screw loosening.
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Concepts | Keywords |
---|---|
Biomechanical | Cortical |
Surgical | Double |
Titanium | Fixation |
Tuberculosis | Group |
Internal | |
Left | |
Lumbosacral | |
Right | |
Rod | |
Screw | |
Spinal | |
Stability | |
Stress | |
System | |
Tuberculosis |
Semantics
Type | Source | Name |
---|---|---|
disease | MESH | spinal tuberculosis |
drug | DRUGBANK | Titanium |
drug | DRUGBANK | Coenzyme M |
disease | MESH | osteoarticular tuberculosis |
disease | MESH | kyphosis |
drug | DRUGBANK | Isoniazid |
drug | DRUGBANK | Rifampicin |
drug | DRUGBANK | Ethambutol |
drug | DRUGBANK | Pyrazinamide |
disease | MESH | tuberculosis |
pathway | KEGG | Tuberculosis |
disease | MESH | complications |
drug | DRUGBANK | Medroxyprogesterone acetate |
disease | MESH | abscesses |
disease | MESH | prosthesis loosening |
disease | MESH | spinal diseases |
disease | MESH | defects |
disease | MESH | lordosis |
disease | MESH | deformity |
drug | DRUGBANK | Guanosine |
drug | DRUGBANK | Sulodexide |
disease | MESH | spondylitis |
pathway | REACTOME | Reproduction |