From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital.

Publication date: Jun 27, 2023

The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37. 4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the employees of a health institution, from acute infection to long COVID. This was a longitudinal study using a retrospective and prospective approach via questionnaires referring to epidemiological investigation, which was the inclusion criteria, and about long-term symptoms. A total of 809 employees were detected with SARS-CoV-2 infection via RT-PCR, 466 of them answered the epidemiological investigation, and 101 completed the Long COVID Symptom Questionnaire. The most commonly affected employees were women (88. 6%) working in patient care (68. 6%). Headache, myalgia, cough, odynophagia, and runny nose were the most frequent symptoms. Only three employees (0. 6%) required hospitalization, while the other employees required outpatient management due to mild symptoms. We identified 19 (4. 1%) cases of reinfection, and 42 (41. 6%) employees reported long-term symptoms, such as myalgia, dyspnea, and headache. Although most cases were mild with good outcomes, long COVID cases identified are noteworthy, as these symptoms may impact quality of life even months after SARS-CoV-2 infection.

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Concepts Keywords
Brazil COVID-19
February healthcare professionals
Pandemic long COVID
Pcr occupational medicine


Type Source Name
disease MESH Long COVID
disease MESH SARS-CoV-2 Infection
pathway REACTOME SARS-CoV-2 Infection
disease IDO country
disease IDO acute infection
disease IDO symptom
disease VO nose
disease MESH reinfection
disease IDO quality
disease MESH infection
drug DRUGBANK Coenzyme M
disease VO protocol
drug DRUGBANK Etoperidone
disease VO Severe acute respiratory syndrome coronavirus 2
disease VO frequency
disease MESH Back pain
disease MESH Chest pain
disease MESH Sweating
disease MESH arthralgia
disease VO mouth
disease MESH tachycardia
disease MESH hypertension
disease MESH comorbidity
disease MESH asthma
pathway KEGG Asthma
disease MESH hypothyroidism
disease MESH obesity
disease MESH death
disease MESH insomnia
disease MESH critically ill
disease VO vaccination
disease VO population
disease MESH Allergy
disease VO USA
disease IDO algorithm
disease VO efficient
disease MESH Post Infectious Disorders

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