Post-Severe-COVID-19 Cardiopulmonary Rehabilitation: A Comprehensive Study on Patient Features and Recovery Dynamics in Correlation with Workout Intensity.

Publication date: Jun 29, 2023

The aftermath of severe COVID-19 frequently involves considerable cardiopulmonary damage, necessitating rehabilitation. This study aimed to evaluate the impact of COVID-19 on cardiopulmonary health and assess the effectiveness of various rehabilitative interventions. Conducted between September 2021 and September 2022, this prospective study included patients who had been diagnosed with severe COVID-19 and admitted at the “Victor Babes” Infectious Diseases and Pulmonology Hospital, Timisoara, Romania. The patients were stratified into low- and high-intensity rehabilitation groups. The rehabilitation protocols were individually tailored, and the patient recovery was closely monitored over a 3-month period. Our cohort comprised 84 patients, with a mean age of 56. 3 years for the low-intensity group (n = 42) and 53. 1 years for the high-intensity group (n = 42). Both groups showed significant improvements in the lung injury area, need for oxygen supplementation, ejection fraction, systolic pulmonary artery pressure, and forced vital capacity. Additionally, considerable enhancements were observed in maximal voluntary ventilation, FEV1, FEV1/FVC ratio, peak expiratory flow, and forced expiratory flow at 25-75%. The work intensity also demonstrated substantial improvements from the initial testing to the 3-month mark in both groups. This study provides evidence that personalized, targeted rehabilitation strategies can improve long-term cardiopulmonary health in patients recovering from severe COVID-19, proving both low-intensity and high-intensity training as sufficient to improve heart and lung function if performed correctly and over a relatively short duration of 3 months. The study findings underscore the importance of implementing comprehensive cardiopulmonary rehabilitation protocols in the care of post-COVID-19 patients and highlight the value of stratified rehabilitation intensity based on individual patient dynamics and recovery features.

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Concepts Keywords
Cardiopulmonary cardiopulmonary rehabilitation
High COVID-19
Month SARS-CoV-2
Rehabilitative

Semantics

Type Source Name
disease MESH COVID-19
disease VO effectiveness
disease MESH Infectious Diseases
disease MESH lung injury
drug DRUGBANK Oxygen
disease MESH maximal voluntary ventilation
drug DRUGBANK Coenzyme M
disease MESH Respiratory Diseases
disease VO ReCOV
disease MESH post acute COVID 19 syndrome
disease MESH infection
disease MESH complications
disease VO effective
disease VO organization
disease VO vaccination
disease VO protocol
drug DRUGBANK Aspartame
disease IDO history
disease MESH abnormalities
disease VO pregnant women
disease MESH myocardial infarction
disease MESH unstable angina
disease MESH heart failure
disease MESH COPD
disease MESH asthma
pathway KEGG Asthma
disease MESH pulmonary hypertension
disease MESH pneumonia
disease MESH respiratory infections
disease MESH cognitive impairments
drug DRUGBANK Medical air
disease MESH acute respiratory distress syndrome
disease MESH postures
disease VO frequency
disease VO device
drug DRUGBANK Isoxaflutole
disease MESH lifestyle
disease IDO blood
drug DRUGBANK L-Alanine
drug DRUGBANK Creatinine
disease VO volume
disease VO population
disease VO vaccine
disease VO unvaccinated
disease MESH Overweight
disease VO vaccinated
disease VO SpaP

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