RT-qPCR-Based Assessment of the Efficacy of 222 nm UVC Irradiation in Reducing SARS-CoV-2 Surface Contamination.

Publication date: Jul 03, 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has emerged as a serious threat to human health worldwide. The effective disinfection of surfaces contaminated with SARS-CoV-2 may help prevent its spread. The aim of this study is to determine the duration required for viral RNA elimination by 222 nm far ultraviolet light using RT-qPCR as a tool. This study investigated the effect of 222 nm UVC irradiation on SARS-CoV-2 RNA in an in vitro experiment. The results showed that the copy number of SARS-CoV-2 RNA did not change even after 300 s of 222 nm UVC irradiation at 0. 1 mW/cm, but extending the exposure to more than 600 s reduced the number of copies of SARS-CoV-2 virus significantly. However, to fully validate the results and enhance the robustness of the findings, it is crucial to increase the number of samples analyzed in future experiments.

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Concepts Keywords
Basel RT-qPCR
Coronavirus SARS-CoV-2


Type Source Name
disease VO Severe acute respiratory syndrome coronavirus 2
disease MESH causes
disease MESH coronavirus disease 2019
disease VO effective
disease VO Viruses
disease MESH infection
disease VO organization
drug DRUGBANK Medical air
drug DRUGBANK Coenzyme M
disease VO dose
disease IDO bactericidal
drug DRUGBANK Gold
disease IDO assay
disease VO time
disease VO frequency
disease VO titer
disease MESH emergency
disease VO USA
disease VO gene
disease VO protocol
disease IDO process
disease VO viability
disease VO viable
disease MESH Obsessive Compulsive Disorder
disease IDO healthcare facility
disease VO effectiveness

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