An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan.

Publication date: Nov 01, 2023

Measles is a highly contagious infection that leads to many serious complications. Despite the significant global effort to eradicate it, it still represents a major threat due to suboptimal vaccination coverage, especially after the coronavirus disease 2019 (COVID-19) pandemic that affected all routine childhood vaccinations. One of its fatal complications, which has been reported a few times in the literature, is hemophagocytic lymphohistiocytosis (HLH). We discuss a case of a 14-month-old unvaccinated female patient who developed measles-induced HLH and was treated with intravenous immunoglobulins (IVIG) and steroids; unfortunately, she developed multiorgan failure and passed away before chemotherapy could be initiated.

Concepts Keywords
Childhood hemophagocytic lymphohistiocytosis (hlh)
Coronavirus measles
Fatal pediatrics
Global vaccination
Lymphohistiocytosis viruses


Type Source Name
disease MESH Measles
pathway KEGG Measles
disease MESH Infection
disease VO report
disease MESH Hemophagocytic Lymphohistiocytosis
disease MESH complications
disease VO vaccination coverage
disease MESH coronavirus disease 2019
disease VO unvaccinated
drug DRUGBANK Immune Globulin Human
disease VO vaccination
disease VO Viruses

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