Prevalence of SARS-CoV-2 infection among US blood donors by industry, May-December 2021.

Publication date: Dec 04, 2023

Work is a social determinant of health that is often overlooked. There are major work-related differences in the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and death, but there have been few analyses of infection rates across industry groups. To date, only one national assessment of SARS-CoV-2 infection prevalence by industry based on self-report has been completed. No study has looked at seroprevalence of COVID-19 by industry. During May-December 2021, blood donors with SARS-CoV-2 antinucleocapsid testing were sent an electronic survey about their work. Free-text industry responses were classified using the North American Industry Classification System. We estimated seroprevalence and 95% confidence intervals (CIs) of SARS-CoV-2 infection by industry. Of 57,726 donors, 7040 (12%, 95% CI: 11. 9%-12. 5%) had prior SARS-CoV-2 infection. Seroprevalence was highest among Accommodation & Food Services (19. 3%, 95% CI: 17. 1%-21. 6%), Mining, Quarrying, and Oil and Gas Extraction (19. 2%, 95% CI: 12. 8%-27. 8%), Healthcare & Social Assistance (15. 6%, 95% CI: 14. 9%-16. 4%), and Construction (14. 7%, 95% CI: 13. 1%-16. 3%). Seroprevalence was lowest among Management of Companies & Enterprises (6. 5%, 95% CI: 3. 5%-11. 5%), Professional Scientific & Technical Services (8. 4%, 95% CI: 7. 7%-9. 0%), and Information (9. 9%, 95% CI: 8. 5%-11. 5%). While workers in all industries had serologic evidence of SARS-CoV-2 infection, certain sectors were disproportionately impacted. Disease surveillance systems should routinely collect work characteristics so public health and industry leaders can address health disparities using sector-specific policies.

Concepts Keywords
Coronavirus blood donors
December COVID-19
Healthcare industry
Professional SARS-CoV-2


Type Source Name
disease MESH SARS-CoV-2 infection
pathway REACTOME SARS-CoV-2 Infection
disease VO Severe acute respiratory syndrome coronavirus 2
disease MESH infection
disease MESH death
disease VO report
disease IDO blood

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