AI Finds Women and Men Differ with Respect to Brain Organization and Function

Publication date: Feb 18, 2024

Menon is senior author of the team’s published study in PNAS, titled, -Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization. ” -. .. our understanding of sex differences in human functional brain organization and their behavioral consequences has been hindered by inconsistent findings and a lack of replication. ” -Critically, the brain features identified by XAI that reliably distinguished functional brain organization between sexes also predicted unique cognitive profiles in females and males,” the authors commented. -Identifying consistent and replicable sex differences in the healthy adult brain is a critical step toward a deeper understanding of sex-specific vulnerabilities in psychiatric and neurological disorders. ” That tells me that overlooking sex differences in brain organization could lead us to miss key factors underlying neuropsychiatric disorders. ” The model’s success suggests that detectable sex differences do exist in the brain, but that they hadn’t been picked up reliably before. Their findings, the team suggested, -. .. may therefore offer a template for investigations of sex differences in vulnerability to individual psychiatric and neurological disorders. “

Concepts Keywords
Chromosomes Brain
Cocktail Cognitive
Longstanding Differences
Neuroscience Disorders
Psychopathology Findings


Type Source Name
disease MESH psychiatric disorders
disease MESH autism
disease MESH attention deficit disorders
disease MESH schizophrenia
disease MESH sequelae
disease MESH Parkinson’s disease
disease MESH neurological disorders
drug DRUGBANK Tropicamide
drug DRUGBANK Nonoxynol-9
drug DRUGBANK Spinosad
drug DRUGBANK Etoperidone

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