Publication date: Jun 19, 2024
“”My lab and my collaborators have been working on discovering Parkinson’s biomarkers using cerebral spinal fluid, but we found it is quite challenging,” he said. “We know that isolated REM sleep disorder is a strong predictor of the disease and we wanted to see if maybe there is something in common,” Bartl said. This is much easier to get samples from patients and less invasive. It’s not just that they are at risk, but they already have blood that indicates the pathological processes in Parkinson’s disease have already taken place. For example, drugs can modify Wnt-signaling pathways in oncology thus may be of interest to the PD field. The study was funded by the Michael J. “Our panel of proteins is also more dynamic and involves the pathophysiology. “Of note, most of the markers also robustly correlated with clinical scores on the Unified Parkinson’s Disease Rating Scale and Mini-Mental State Examination.
| Concepts | Keywords |
|---|---|
| Baltimore | Assay |
| Biomarker | Bartl |
| Fox | Biomarkers |
| June | Blood |
| Parkinson | Diagnosis |
| Foundation | |
| Healthy | |
| Identify | |
| Motor | |
| Neurology | |
| Panel | |
| Parkinson | |
| Predict | |
| Study | |
| Years |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Parkinson’s disease |
| disease | MESH | dementia |
| disease | MESH | REM sleep behavior disorder |
| disease | MESH | sleep disorder |
| disease | MESH | pathological processes |
| disease | MESH | movement disorders |
| disease | MESH | syndrome |