Publication date: Jun 19, 2024

Both groups were examined over a period of ten years. In the study, 23 proteins in the blood samples were identified as possible biomarkers for Parkinson’s disease using mass spectrometry. In a first step, proteins in blood samples from Parkinson’s patients at the Paracelsus-Elena-Klinik Kassel and healthy study participants were analyzed using modern mass spectrometry. At the time of the first blood sample, none of the subjects with sleep behavior disorder had motor signs of Parkinson’s disease. It was possible to identify 23 proteins that showed differences between the diseased and healthy participants and could therefore be considered biomarkers for the disease. The results have been published in the renowned journal Nature Communications. Parkinson’s disease is the second most common neurodegenerative disease and is becoming increasingly common in the population. “By determining eight proteins in the blood, we can identify potential Parkinson’s patients several years in advance. In addition to motor symptoms such as slowness of movement, increased muscle tension and tremors, those affected also show non-motor symptoms such as olfactory and sleep disorders and depression.

Semantics

Original Article