Publication date: Jun 18, 2024
Vitiligo, a common dermatological disorder in Saudi Arabia, is associated with significant psychological impacts. This study explores the relationship between vitiligo and the severity of Major Depressive Disorder (MDD), highlighting the broader implications on mental health among affected individuals. To assess the prevalence and predictors of depression among adult vitiligo patients, and to examine the relationship between MDD severity and vitiligo. Employing a cross-sectional design, the research utilized the Vitiligo Area Severity Index (VASI) and the Patient Health Questionnaire-9 (PHQ-9) to measure the extent of vitiligo and depression severity respectively. The study involved 340 diagnosed vitiligo patients from various healthcare settings. Logistic and ordinal regression analysis were applied to evaluate the impact of sociodemographic variables and vitiligo types on MDD severity. The prevalence of MDD was 58. 8% (200 out of 340 participants). Depression severity varied notably: 24. 7% of patients experienced mild depression, 31. 1% moderate, 22. 6% moderately severe, and 21. 6% severe depression. Female patients had higher odds of severe depression compared to males (aOR = 3. 14, 95% CI: 1. 93-5. 1, P < .001). Age was inversely related to depression severity, with patients over 60 years showing significantly lower odds (aOR = 0. 1, 95% CI: 0. 03-0. 39, P < .001). Lower income was associated with higher depression severity (aOR = 10. 2, 95% CI: 3. 25-31. 8, P < .001). Vitiligo types also influenced depression severity; vulgaris (aOR = 5. 3, 95% CI: 2. 6-10. 9, P < .001) and acrofacial vitiligo (aOR = 2. 8, 95% CI: 1. 5-5. 1, P < .001) were significantly associated with higher depression levels compared to focal vitiligo. The findings suggest that vitiligo contributes to an increased risk of severe depression, highlighting the need for integrated dermatological and psychological treatment approaches to address both the physical and mental health aspects of the disease.
| Concepts | Keywords |
|---|---|
| Depressive | Aor |
| Dermatol | Ci |
| Increased | Cross |
| Saudi | Depression |
| Sociodemographic | Depressive |
| Dermatological | |
| Disorder | |
| Higher | |
| Major | |
| Mdd | |
| Relationship | |
| Sectional | |
| Severe | |
| Severity | |
| Vitiligo |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Vitiligo |
| disease | MESH | Major Depressive Disorder |