Porcine respiratory coronavirus genome sequences; comparisons and relationships to transmissible gastroenteritis viruses.

Publication date: Jul 01, 2024

Porcine respiratory coronavirus (PRCV) was initially detected in Europe, and later in the United States of America (US), in the 1980s. In this study we obtained and compared PRCV sequences from Europe and the US, and investigated how these are related to transmissible gastroenteritis virus (TGEV) sequences. The whole genome sequences of Danish (1/90-DK), Italian (PRCV15087/12 III NPTV Parma), and Belgian PRCV (91V44) strains are presented. These sequences were aligned with nine other PRCV sequences from Europe and the US, and 43 TGEV sequences. Following alignment of the PRCV sequences, it was apparent that multiple amino acid variations in the structural proteins were distinct between the European and US strains. The alignments were used to build phylogenetic trees to infer the evolutionary relationships between the strains. In these trees, the European PRCV strains clustered as a separate group, whereas the US strains of PRCV all clustered with TGEVs.

Concepts Keywords
Coronavirus Animals
Danish Coronavirus
Italian Coronavirus Infections
Prcv15087 Coronaviruses
Virology Europe
Genome, Viral
Phylogeny
Phylogeny
Porcine respiratory coronavirus
PRCV
Sequence analysis
Swine
Swine Diseases
TGEV
Transmissible gastroenteritis virus
Transmissible gastroenteritis virus
United States

Semantics

Type Source Name
disease MESH gastroenteritis
disease VO Viruses
disease VO Transmissible gastroenteritis virus
disease MESH Coronavirus Infections
disease MESH Gastroenteritis Transmissible of Swine
disease MESH Swine Diseases

Original Article

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