Publication date: Sep 01, 2024
A 67-year-old woman with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis was not vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and was on multiple immunosuppressive drugs. She was hospitalized because of interstitial shadowing in the lungs and diagnosed with persistent coronavirus disease 2019 (COVID-19). Despite treatment with a recombinant monoclonal antibody and antivirals, her symptoms persisted and she lacked a specific antibody response. She tested negative for SARS-CoV-2 antigen after the second antiviral treatment, and a subsequent chest radiograph showed improvement. However, the antibody levels did not change. This case highlights the importance of careful monitoring of the SARS-CoV-2 antigen and antibody levels during COVID-19 treatment in patients with immunosuppression.
Semantics
Type | Source | Name |
---|---|---|
disease | MESH | coronavirus disease 2019 |
disease | MESH | vasculitis |
disease | VO | vaccinated |
disease | VO | Severe acute respiratory syndrome coronavirus 2 |
disease | IDO | immunosuppression |
disease | MESH | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis |
disease | MESH | Immunocompromised Host |
drug | DRUGBANK | Ritonavir |