Shift in Demographic Involvement and Clinical Characteristics of COVID-19 From Wild-Type SARS-CoV-2 to the Delta Variant in the Indian Population: In Silico Analysis.

Shift in Demographic Involvement and Clinical Characteristics of COVID-19 From Wild-Type SARS-CoV-2 to the Delta Variant in the Indian Population: In Silico Analysis.

Publication date: Oct 08, 2024

The Delta variant (B. 1.617. 2) was considered the most dangerous SARS-CoV-2 strain; however, in-depth studies on its impact based on demographic and clinical characteristics of COVID-19 are scarce. We aimed to investigate the shift in demographic and clinical characteristics of the COVID-19 pandemic with the emergence of the SARS-CoV-2 Delta variant compared with the wild-type (WT) strain (B. 1). A cross-sectional study of COVID-19 cases in the Indian population caused by the WT strain (B. 1) and Delta variant of SARS-CoV-2 was performed. The viral genomic sequence metadata containing demographic, vaccination, and patient status details (N=9500, N=6238, N=3262) were statistically analyzed. With the Delta variant, in comparison with the WT strain, a higher proportion of young individuals (

Concepts Keywords
Pandemic COVID-19
Vaccination demographic shift
Viral epidemiology
Young genomic analysis
pandemic
population studies
SARS-CoV-2
severity of illness
variant
virus

Semantics

Type Source Name
disease MESH COVID-19

Original Article

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