Publication date: Oct 11, 2024
If it [quetiapine] works, it works the next day or the day after, whereas with pimavanserin you have to wait for a week or two. “Our general impression in the United States is that pimavanserin has a slower uptake in efficacy as compared with quetiapine. So that’s why an additional drug this one has a slightly different mechanism is incredibly helpful in the clinic because not everyone responds to quetiapine. There was one unrelated fatal stroke in the quetiapine group. “Katzenschlager pointed out that pimavanserin is not approved in Europe and that the present study was conducted for regulatory purposes in India. Mane is an employee of Sun Pharma Laboratories. Katzenschlager reported having no relevant financial relationships. “We did discuss this with most of our investigators, and they gave the same reason.
| Concepts | Keywords |
|---|---|
| 01treatment | Day |
| Austria | Days |
| Hospitalization | Drug |
| Nighttime | Drugs |
| Efficacy | |
| Group | |
| Improvement | |
| Mane | |
| Mean | |
| Parkinson | |
| Pimavanserin | |
| Psychosis | |
| Quetiapine | |
| Said | |
| Sleep |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Neurodegenerative Disorders |
| disease | MESH | stroke |
| disease | MESH | nasopharyngitis |
| disease | MESH | delusions |
| disease | MESH | hallucinations |
| disease | MESH | Movement Disorders |
| disease | MESH | dementia |
| disease | MESH | cognitive impairment |
| disease | MESH | drooling |
| disease | MESH | agranulocytosis |
| drug | DRUGBANK | Clozapine |
| disease | MESH | Parkinson’s disease |
| drug | DRUGBANK | Quetiapine |
| disease | MESH | Psychosis |
| drug | DRUGBANK | Tropicamide |
| drug | DRUGBANK | Pimavanserin |