Atopic Dermatitis and Autism Spectrum Disorders: Common Role of Environmental and Clinical Co-Factors in the Onset and Severity of Their Clinical Course.

Publication date: Aug 16, 2024

Increasing evidence suggests an association between atopic dermatitis, the most chronic inflammatory disease of the skin, and autism spectrum disorders, which are a group of neurodevelopmental diseases. Inflammation and immune dysregulation associated with genetic and environmental factors seem to characterize the pathophysiological mechanisms of both conditions. We conducted a literature review of the PubMed database aimed at identifying the clinical features and alleged risk factors that could be used in clinical practice to predict the onset of ASD and/or AD or worsen their prognosis in the context of comorbidities.

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Concepts	Keywords
Chronic	ADHD
Dermatitis	atopic dermatitis
Environmental	Autism Spectrum Disorder
Genetic	autism spectrum disorders
Neurodevelopmental	Comorbidity
	Dermatitis, Atopic
	exposome
	genetic
	Humans
	Risk Factors

Semantics

Type	Source	Name
disease	MESH	Atopic Dermatitis
disease	MESH	Autism Spectrum Disorders
disease	MESH	Clinical Course
disease	MESH	Inflammation
disease	MESH	ADHD
disease	MESH	Comorbidity