A Prospective, Multicenter, Open-label, Randomized, Actively Controlled, Parallel-group Phase 3 Clinical Trial to Evaluate Efficacy, Safety, and Tolerability of IMA203 Versus Investigator’s Choice of Treatment in Patients With Previously Treated, Unresectable or Metastatic Cutaneous Melanoma (ACTengine® IMA203-301)

A Prospective, Multicenter, Open-label, Randomized, Actively Controlled, Parallel-group Phase 3 Clinical Trial to Evaluate Efficacy, Safety, and Tolerability of IMA203 Versus Investigator’s Choice of Treatment in Patients With Previously Treated, Unresectable or Metastatic Cutaneous Melanoma (ACTengine® IMA203-301)

Publication date: Jan 16, 2025

This clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and tolerability of treatment with IMA203 administered at the recommended phase 2 dose versus investigator’s choice of treatment in patients with previously treated, unresectable or metastatic cutaneous melanoma.

Concepts Keywords
Chemotherapy Choice
Childbearing Clinical
Cyclophosphamide Criteria
Live Cutaneous
Randomized Ima203
Investigator
Melanoma
Metastatic
Patient
Phase
Prior
Treated
Treatment
Trial
Unresectable

Semantics

Type Source Name
disease MESH Melanoma
pathway KEGG Melanoma
disease MESH Disease progression
disease MESH Tumors
disease MESH uveal melanoma
disease MESH squamous cell carcinoma
disease MESH carcinoma in situ
disease MESH autoimmune disease
disease MESH hypersensitivity
disease MESH contraindications
disease MESH HIV infection
pathway REACTOME HIV Infection
disease MESH infection
disease MESH psychiatric disorders
disease MESH substance dependence
disease MESH ascites
disease MESH pericardial effusion
disease MESH brain metastases
disease MESH Melanoma Cutaneous Malignant

Original Article

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