Publication date: Mar 21, 2025
Purpose The study aimed to assess the value of event-related potentials (ERP) of executive functions in distinguishing between attention deficit hyperactivity disorder (ADHD) and ADHD combined with autism spectrum disorder (ADHD&ASD). Methods This retrospective analysis included 204 participants divided into three groups: ADHD&ASD (64/204), ADHD (70/204), and typical development (TD) (70/204). Neuropsychological tests, including the Digit Span Test, Behavior Rating Inventory of Executive Function (BRIEF), Trail Making Test at its Chinese equivalent version, the Shape Trail Test (STT), and the Stroop Color Word Interference Test, were compared across groups. ERP measures, such as latency and amplitude at the frontal zone (Fz), central zone (Cz), and parietal zone (Pz), along with reaction times and target stimulus hits using an oddball paradigm, were analyzed. Post-hoc analyses and receiver operating characteristic (ROC) curves identified key indicators for distinguishing ADHD from ADHD&ASD. Results Significant differences were found in ERP and BRIEF indicators (P
Open Access PDF
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | ADHD |
| disease | MESH | comorbidity |
| disease | MESH | autism spectrum disorder |
| drug | DRUGBANK | Saquinavir |
| disease | MESH | Cognitive Disorders |
| drug | DRUGBANK | Coenzyme M |
| disease | MESH | Mental Disorders |
| drug | DRUGBANK | Dihydrostreptomycin |
| disease | MESH | impulsivity |
| drug | DRUGBANK | Methionine |
| disease | MESH | intellectual disability |
| disease | MESH | epilepsy |
| disease | MESH | Autism |
| disease | MESH | anxiety |
| disease | MESH | confusion |
| drug | DRUGBANK | Silver |
| drug | DRUGBANK | Ethanol |
| drug | DRUGBANK | Tropicamide |