Efficacy of pembrolizumab monotherapy for advanced gingival malignant melanoma: A case report.

Publication date: Mar 22, 2025

Oral malignant melanoma specifically denotes a rare subtype of melanoma originating in oral mucosa, characterized by a generally poor prognosis. Inhibitors targeting programmed cell death protein-1 or its ligand-1 (PD-1/PD-L1) have become widely accepted as primary treatments for malignant melanoma. The current report describes a unique case of advanced gingival malignant melanoma treated with pembrolizumab monotherapy in a 67-year-old Asian female. The report comprehensively evaluates the therapeutic potential of pembrolizumab, as well as its immune-related adverse events (irAEs).

Concepts Keywords
Female Case report
Gingival Oral malignant melanoma
Malignant Pembrolizumab
Old
Pembrolizumab

Semantics

Type Source Name
drug DRUGBANK Pembrolizumab
disease MESH malignant melanoma
pathway KEGG Melanoma

Original Article

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