Mental health-promoting intervention models in university students: a systematic review and meta-analysis protocol.

Publication date: Mar 22, 2025

The transition to higher education represents a demanding adaptation process with several socioeconomic factors involved. Mental health problems among university students have been worsening since the beginning of the COVID-19 pandemic. Our objective is to create scientific evidence about the models of mental health-promoting interventions among higher education students applied in academic environments, as well as their effectiveness. We aim to synthesise the scientific evidence on the models of an intervention promoting mental health among university students applied in academic environments as well as their results. A systematic review of the literature will be conducted. The research will be carried out using the EBSCO databases (CINAHL Complete, MEDLINE Complete, Psychology and Behavioral Sciences Collection), PubMed and Scopus. The research strategy includes the following MeSH or similar terms: Universities [Mesh], Students [Mesh], Education [Mesh], Undergraduate, “Higher Education”, Universit*, College, Student*; “Psychosocial intervention” [Mesh], “Non-pharmacological”, “Intervention model*”, “Mental health promotion program*”, Intervention*; “Randomized Controlled Trial”, RCT; “Mental health” [Mesh], Depression [Mesh], Anxiety [Mesh], “Stress, psychological” [Mesh], “Quality of life” [Mesh], and “Psychological well-being” [Mesh]. All experimental studies with mental health-promoting interventions for university students that were published between January 2017 and November 2024 in English will be eligible. Two independent reviewers will apply the inclusion and exclusion criteria, analyse the quality of the data and extract it for synthesis. Disagreements will be resolved by a third reviewer. All randomised controlled trial studies with interventions in university students and their efficacy (with means and SD) will be included in the systematic review of the literature. The standardised mean difference will be used as the effect size to standardise individual results. Sensitivity analysis, subgroup analysis and meta-regression will be conducted to explore the causes of heterogeneity and the robustness of the results. Ethical approval is not required for this study as it is based on the review of previously published data. The results will be disseminated through publication in peer-reviewed journals and presentations at academic conferences, as well as in events organised by student associations. CRD42022359608.

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Concepts Keywords
Crd42022359608 Anxiety disorders
Medline COVID-19
Pandemic Depression & mood disorders
Psychology Health Promotion
Universities Humans
Mental Health
MENTAL HEALTH
Meta-Analysis as Topic
Psychosocial Intervention
Research Design
SARS-CoV-2
Stress, Psychological
Students
Universities

Semantics

Type Source Name
disease IDO intervention
disease IDO process
disease MESH COVID-19 pandemic
disease MESH Depression
disease MESH Anxiety
disease MESH Stress psychological
disease IDO quality
disease MESH Psychological well-being
disease MESH causes
disease MESH uncertainty
disease MESH obsessive compulsive disorder
disease MESH post traumatic stress disorder
drug DRUGBANK Indoleacetic acid
disease MESH mental disorder
disease IDO history
disease IDO country
drug DRUGBANK Trestolone
disease MESH SD1
pathway REACTOME Translation
disease MESH Substance Use
drug DRUGBANK (S)-Des-Me-Ampa
disease MESH psychological distress
drug DRUGBANK Etoperidone
disease MESH Anxiety disorders
disease MESH mood disorders

Original Article

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