Publication date: Mar 24, 2025

For example, it wasn’t to directly measure PTEN activity in an intact brain, which would greatly help our understanding of its role in health and disease”. Dr. This groundbreaking technology, which combines advancements in genetic tools and microscopy, will allow scientists to gain deeper insights into why PTEN is so crucial for normal brain development. There is growing evidence that mutations in PTEN, which reduce its activity, contribute to diseases like autism, macrocephaly, cancer, and epilepsy. Despite the critical role PTEN plays in cellular function, scientists have had limited tools to measure its activity. This process is crucial for normal development, as cells go through periods of precise growth regulation. A novel scientific method developed at Tel Aviv University promises to accelerate our understanding of the gene PTEN, a key player in cellular growth. Tal Laviv explains: “Many studies have shown that PTEN is essential for regulating cell growth in the brain by providing a stop signal.

Semantics

Original Article