Placental Epigenetic Changes may Increase Schizophrenia Risk

Placental Epigenetic Changes may Increase Schizophrenia Risk

Publication date: Mar 24, 2025

Decades ago, scientists began to investigate the association between problems in fetal development and schizophrenia. In pregnancy, the placenta is the link between mother and child, and this prenatal environment can have huge influences on the development of the fetus. Changes in the intrauterine environment have been associated with cardiovascular, metabolic, and neurodevelopmental disorders. Instead, epigenetics can work through structural changes in the genome, or the attachment or removal of methyl groups. Knowing more about the basis of such illnesses will help scientists create better therapeutics or potentially, preventive measures. Sources: University of Basque Country, Nature Communications

Concepts Keywords
Autism Decades
Decades Disorder
Dna Disorders
Mother Epigenetic
Therapeutics Groups
Influences
Learn
Link
Methylation
Neurodevelopmental
Placenta
Placental
Prenatal
Risk
Schizophrenia

Semantics

Type Source Name
disease MESH Schizophrenia
disease MESH neurodevelopmental disorders
pathway REACTOME Methylation
pathway REACTOME DNA methylation
disease MESH bipolar disorder
disease MESH major depressive disorder
disease MESH attention deficit hyperactivity disorder
disease MESH autism spectrum disorder
disease MESH depression
drug DRUGBANK Tropicamide

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