Publication date: Mar 24, 2025

Infants with the disease had increased risks for individual psychiatric disorders, including intellectual disabilities (HR, 2. 19), nervous and stress-related disorders (HR, 1. 43), and behavioural disorders (HR, 1. 46). Maternal gestational diabetes, premature birth of infants, and low maternal education further increased the risk of developing psychiatric disorders through adolescence. Overall, the cumulative incidence of psychiatric disorders was 21. 1% in infants with invasive group B Streptococcus disease vs 16. 2% in control individuals. TOPLINE: Invasive group B Streptococcus disease in early infancy increased the risk for psychiatric disorders through adolescence. Parameters affecting the development of psychiatric disorders, including sex, prematurity, year of birth, maternal age at delivery, maternal education, and maternal income, were identified. Successful prevention of iGBS would decrease not only the mortality attributable to iGBS but also the long-term risk of psychiatric disorders caused by the infection,” the authors wrote. Overall, data from 1548 infants diagnosed with invasive group B Streptococcus disease between 1997 and 2020 were included, of whom 87. 7% had sepsis and 12. 3% had meningitis.

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