Publication date: Mar 19, 2025
The goal of this study is to learn about the safety of different doses of MK-4700 and if people tolerate them. The study will also measure what happens in a person’s body over time when MK-4700 is given alone or with pembrolizumab (MK-3475) in order to find a dose that is safe, tolerated, and may work to treat certain types of cancer.
| Concepts | Keywords |
|---|---|
| Cancer | Cervical Cancer |
| Nervous | Melanoma |
| Organ | Renal Cell Carcinoma |
| Pharmacokinetics | Urothelial Carcinoma |
Semantics
| Type | Source | Name |
|---|---|---|
| drug | DRUGBANK | Pembrolizumab |
| disease | MESH | Tumors |
| disease | MESH | head and neck squamous cell carcinoma |
| disease | MESH | melanoma |
| pathway | KEGG | Melanoma |
| disease | MESH | non-small cell lung cancer |
| pathway | KEGG | Non-small cell lung cancer |
| disease | MESH | cervical cancer |
| disease | MESH | triple negative breast cancer |
| disease | MESH | carcinoma |
| disease | MESH | renal cell carcinoma |
| pathway | KEGG | Renal cell carcinoma |
| disease | MESH | Kaposi’s sarcoma |
| disease | MESH | Multicentric Castleman’s |
| disease | MESH | metastases |
| disease | MESH | carcinomatous |
| disease | MESH | autoimmune disease |
| disease | MESH | pneumonitis |
| disease | MESH | interstitial lung disease |
| disease | MESH | infection |
| disease | MESH | Hepatitis B |
| pathway | KEGG | Hepatitis B |
| drug | DRUGBANK | Hepatitis B Vaccine (Recombinant) |
Original Article
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