Two-tier nature inspired optimization-driven ensemble of deep learning models for effective autism spectrum disorder diagnosis in disabled persons.

Publication date: Mar 24, 2025

Autism spectrum disorder (ASD) includes a varied set of neuropsychiatric illnesses. This disorder is described by a definite grade of loss in social communication, academic functioning, personal contact, and limited and repetitive behaviours. Individuals with ASD might perform, convey, and study in a different way than others. ASDs naturally are apparent before age 3 years, with related impairments affecting manifold regions of a person’s lifespan. Deep learning (DL) and machine learning (ML) techniques are used in medical research to diagnose and detect ASD promptly. This study presents a Two-Tier Metaheuristic-Driven Ensemble Deep Learning for Effective Autism Spectrum Disorder Diagnosis in Disabled Persons (T2MEDL-EASDDP) model. The main aim of the presented T2MEDL-EASDDP model is to analyze and diagnose the different stages of ASD in disabled individuals. To accomplish this, the T2MEDL-EASDDP model utilizes min-max normalization for data pre-processing to ensure that the input data is scaled to a uniform range. Furthermore, the improved butterfly optimization algorithm (IBOA)-based feature selection (FS) is utilized to identify the most relevant features and reduce dimensionality efficiently. Additionally, an ensemble of DL holds three approaches, namely autoencoder (AE), long short-term memory (LSTM), and deep belief network (DBN) approach is employed for analyzing and detecting ASD. Finally, the presented T2MEDL-EASDDP model employs brownian motion (BM) and directional mutation scheme-based coati optimizer algorithm (BDCOA) techniques to fine-tune the hyperparameters involved in the three ensemble methods. A wide range of simulation analyses of the T2MEDL-EASDDP technique is accomplished under the ASD-Toddler and ASD-Adult datasets. The performance validation of the T2MEDL-EASDDP method portrayed a superior accuracy value of 97. 79% over existing techniques.

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Concepts Keywords
Academic Algorithms
Autism Autism Spectrum Disorder
Butterfly Autism spectrum disorder
Neuropsychiatric Butterfly optimization algorithm
Optimizer Deep Learning
Deep learning
Disabled persons
Humans
Machine Learning
Male
Metaheuristic
Persons with Disabilities

Semantics

Type Source Name
disease MESH autism spectrum disorder
disease MESH developmental disabilities
disease MESH communication disorders
drug DRUGBANK Coenzyme M
disease MESH mental disorders
disease MESH depression
disease MESH aids
disease MESH autism
drug DRUGBANK Pidolic Acid
disease MESH anxiety
drug DRUGBANK Aspartame
drug DRUGBANK Flunarizine
drug DRUGBANK Isoxaflutole
drug DRUGBANK Succimer
drug DRUGBANK Coenzyme A
disease MESH confusion
drug DRUGBANK Saquinavir
drug DRUGBANK L-Valine
disease MESH COVID 19
disease MESH Defects
drug DRUGBANK Guanosine
pathway REACTOME Reproduction

Original Article

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