Comparative analysis of demographic, clinical, biochemical, and predictors of mortality in COVID-19 and NON-COVID-19 ARDS patients: A retrospective cohort study.

Publication date: Mar 21, 2025

The COVID-19 pandemic has brought a significant increase in the incidence of acute respiratory distress syndrome (ARDS). This retrospective study aims to compare the differences in demographic, clinical, and biochemical variables and predictive factors in 2 situations of ARDS cause (COVID-19 vs NON-COVID-19) in patients admitted to the intensive care unit. The Mann-Whitney rank-sum test was performed for quantitative variables, and Fisher exact test for qualitative variables. 115 patients with ARDS were enrolled (53 patients with COVID-19 ARDS and 62 NON-COVID-19 ARDS). The COVID-19 ARDS group consisted of 33 male patients (66. 2%), whereas the NON-COVID-19 ARDS group had 25 male patients (40. 3%) (P = . 0248). The median and interquartile age difference of the COVID-19 ARDS group was 64. 0 [52. 0-69. 5], and non-COVID-19 ARDS was 49. 0 [34. 0-63. 0] (P = . 0011). Body mass index, simplified acute physiology score, sequential organ failure assessment, and intensive care unit length of stay, with P-values of .0061, .0002, .0003, and

Concepts Keywords
Baltimore Aged
Organ Body Mass Index
Pandemic COVID-19
Retrospective Female
Hospital Mortality
Humans
Intensive Care Units
Length of Stay
Male
Middle Aged
Organ Dysfunction Scores
Respiratory Distress Syndrome
Retrospective Studies
Risk Factors
SARS-CoV-2

Semantics

Type Source Name
disease MESH COVID-19
disease MESH acute respiratory distress syndrome
disease MESH Organ Dysfunction Scores

Original Article

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