Monitoring reported SARS-CoV-2 variants to assess the status of COVID-19 epidemics in the low epidemic state.

Publication date: Mar 24, 2025

The reported new confirmed cases of Coronavirus Disease 2019 (COVID-19) nowadays have diminished in their usefulness for assessing the pandemic situation. This study aimed to discover the correlation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants recorded by Nextstrain clade and PANGO lineage and the number of new confirmed cases. Percent stacked area charts were utilized to display their development trends. 31 and 1452 variants were named according to Nextstrain clade and PANGO lineage, respectively. The branch step value maintained a stable increase by linear regression analysis. The changing trend in SARS-CoV-2 variants (PANGO lineage) correlated negatively with the number of new confirmed COVID-19 cases through Spearman rank correlation coefficient (17/06/2020-17/11/2021, ρ=-0. 387, P 

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Concepts Keywords
Coronavirus COVID-19
Covid COVID-19 pandemic
Low Epidemics
Pandemic Humans
Monitoring
Nextstrain clade
Pandemics
PANGO lineage
SARS-CoV-2
SARS-CoV-2 variation

Semantics

Type Source Name
disease MESH COVID-19
disease MESH emergency
disease MESH infection
disease MESH infectious diseases
pathway REACTOME Reproduction
disease IDO infectivity
disease MESH viral load
drug DRUGBANK Coenzyme M
disease IDO process
disease MESH measles
pathway KEGG Measles

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