Publication date: Mar 26, 2025

MXenes, a rapidly emerging class of two-dimensional materials, have demonstrated exceptional versatility and functionality across various domains, including microbiology and virology. Recent advancements in MXene synthesis techniques, encompassing both top-down and bottom-up approaches, have expanded their potential applications in pathogen detection, antimicrobial treatments, and biomedical platforms. This review highlights the unique physicochemical properties of MXenes, including their large surface area, tunable surface chemistry, and high biocompatibility, which contribute to their antimicrobial efficacy against bacteria, fungi, and viruses, such as SARS-CoV-2. The antibacterial mechanisms of MXenes, including membrane disruption, reactive oxygen species (ROS) generation, and photothermal inactivation, are discussed alongside hybridization strategies that enhance their bioactivity. Additionally, the challenges and future prospects of MXenes in developing advanced antimicrobial coatings, diagnostic tools, and therapeutic systems are outlined. By addressing current limitations and exploring innovative solutions, this study underscores the transformative potential of MXenes in microbiology, virology, and biomedical applications.

Semantics

Original Article