Publication date: Mar 25, 2025
One hypothesis is that viral “molecular mimics” that resemble the body’s own proteins trigger an immune response against the virus — and healthy tissues get caught in the crossfire. But why the virus might cause the body’s immune system to go haywire remains unknown, making it difficult to develop therapies to avoid autoimmunity. Now, with advanced data analysis and machine learning, scientists have identified a set of COVID-derived molecular mimics that are most likely to be involved in triggering autoimmunity. COVID infection has been linked to higher risk of autoimmune disorders, including rheumatoid arthritis and type 1 diabetes.
| Concepts | Keywords |
|---|---|
| Covid | Autoimmune |
| Diabetes | Autoimmunity |
| Haywire | Body |
| Rheumatoid | Covid |
| Virus | Finds |
| Higher | |
| Immune | |
| Induced | |
| Infection | |
| Linked | |
| Mimics | |
| Molecular | |
| Potential | |
| Risk | |
| Virus |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | immune response |
| disease | MESH | autoimmunity |
| pathway | REACTOME | Immune System |
| disease | MESH | type 1 diabetes |
| pathway | KEGG | Rheumatoid arthritis |
| disease | MESH | rheumatoid arthritis |
| disease | MESH | infection |
| disease | MESH | autoimmune disease |
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