Publication date: Apr 14, 2025
This Randomized Controlled Trial (RCT) aims to assess the effectiveness and acceptability of the Unified Protocol (UP) in an online group format for the treatment of emotional disorders in adults. Participants will be 90 adults (45 in the control group and 45 in the experimental group) with diagnosis of long COVID and comorbid emotional disorders. Participants will be recruited at Hospital Royo Villanova from Zaragoza, Spain. In this study it will be explored whether the changes obtained after the intervention in emotional disorders and cognitive complaints are maintained over 12 months. Additionally, levels of chronic stress will be longitudinally evaluated in the experimental group through accumulated cortisol levels in hair, before and after the application of the UP.
| Concepts | Keywords |
|---|---|
| Depressive | Cognitive Behavioral |
| Hospital | Emotion regulation skills |
| Internet | Emotional Disorders |
| Longcovid | Long COVID-19 |
| Recruiting | Psychological |
| Transdiagnostic | |
| Unified Protocol |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Long COVID |
| disease | IDO | intervention |
| drug | DRUGBANK | Hydrocortisone |
| disease | MESH | SARS-CoV-2 infection |
| pathway | REACTOME | SARS-CoV-2 Infection |
| disease | IDO | acute infection |
| disease | MESH | depression |
| disease | MESH | anxiety |
| disease | MESH | severe mental disorder |
| disease | MESH | personality disorder |
| disease | MESH | bipolar disorder |
| disease | MESH | suicidal ideation |