Publication date: May 22, 2025
Specialized TIL therapy centers can delve into these details during the patient evaluation process. It’s important to remember that TIL therapy is an intensive treatment. An elderly patient with multiple comorbidities who struggles with basic physical activities like climbing stairs might not be able to tolerate the therapy safely. Patients with a lower disease burden and normal LDH levels tend to respond better. Their performance status is also critical; are they functionally well, and what are their comorbidities? The demanding nature of the treatmentwhich involves side effects from the TIL cells themselves, chemotherapy, and IL-2can be significant. While these factors won’t necessarily prevent a referral, they are important starting points for discussion.
| Concepts | Keywords |
|---|---|
| Chemotherapy | Burden |
| Elderly | Candidates |
| Flight | Comorbidities |
| Krishnamurthy | Factors |
| Park | Key |
| Ldh | |
| Melanoma | |
| Multiple | |
| Patient | |
| Process | |
| Referring | |
| Significant | |
| Therapy | |
| Treatment | |
| Tumor |
Semantics
| Type | Source | Name |
|---|---|---|
| drug | DRUGBANK | Tropicamide |
| disease | MESH | Cancer |
| pathway | KEGG | Melanoma |
| disease | MESH | Melanoma |