Validation of the Dutch version of the King’s Parkinson’s disease pain scale.

Publication date: May 21, 2025

Pain in patients with Parkinson’s disease (PD)is often underdiagnosed and, therefore, undertreated. The King’s Parkinson’s Pain Scale (KPPS) is one of the few validated tools specifically designed to assess pain in patients with Parkinson’s disease but lacks a Dutch version. This study aims to validate the KPPS for patients in the Netherlands and to examine which cognitive functions are related to the comprehension of the KPPS. The KPPS was translated into Dutch and validated in 70 patients with PD through internal consistency, convergent and discriminant validity testing. Patients had been diagnosed with PD for an average of 5. 65 years. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). The Dutch KPPS showed acceptable reliability (Cronbach’s alpha = 0. 69), though its factor structure differed from the original. Convergent validity was confirmed via significant correlations with the Numerical Rating Scale (NRS), while discriminant validity was supported through correlations with the Non-Motor Symptoms Scale (NMSS) and EQ-5D-3 L. Verbal memory and abstract thinking showed a tendency toward significance in their association with pain scores. The Dutch KPPS is a reliable and valid tool for assessing pain in Dutch patients with PD, though its structure differs from the original. These differences may reflect variability in pain perception or classification, highlighting the need for further research integrating the PD-PCS framework to refine pain assessment in PD.

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Concepts Keywords
5d Cognition
Dutch Dutch population
Montreal Pain
Parkinson Parkinson’s disease
Undertreated Translation
Validation

Semantics

Type Source Name
disease MESH Parkinson’s disease
pathway REACTOME Reproduction
disease MESH tremor
disease MESH cognitive impairment
drug DRUGBANK Coenzyme M
pathway REACTOME Translation
drug DRUGBANK Trihexyphenidyl
drug DRUGBANK Profenamine
disease MESH anxiety
disease MESH neurological disorders
disease MESH dementia
drug DRUGBANK Dimercaprol
disease MESH movement disorders
drug DRUGBANK Etoperidone
disease MESH education level
disease MESH Depression
drug DRUGBANK Trestolone
disease MESH privacy
disease MESH Musculoskeletal pain
disease MESH Chronic pain
disease MESH edema
disease MESH Restless legs
drug DRUGBANK Pidolic Acid
drug DRUGBANK Aspartame
drug DRUGBANK Levodopa

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