GABAergic receptors and essential oils in anxiety and depression: a scientometric analysis.

Publication date: May 22, 2025

This review aims to map and analyse scientific production on the effect of essential oils and their isolated compounds on GABAergic receptors with a focus on the treatment of anxiety and depression. Publications were selected from the Web of Science following the PRISMA guidelines from October 1945 to March 2024. Analysis of publication trends, geographic distribution, keywords, and influential articles was carried out using the CiteSpace and Bibliometrix tools. The results indicate that research on the topic is a recent trend, with only eight articles published before 2003 and a significant increase in publications during the SARS-CoV-2 pandemic. The main areas of interest were Medicinal Chemistry, Plant Sciences, and Integrative and Complementary Medicine, with Brazil and China leading the publications. The study also highlights a growing interest in scientifically validating natural therapies for safer and more effective treatment options.

Concepts Keywords
Brazil aromatherapy
China bibliometric analysis
Medicine Complementary therapy
October mental health
Pandemic neurotransmitters

Semantics

Type Source Name
disease MESH anxiety
disease MESH depression
disease IDO production

Original Article

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