Publication date: Jun 25, 2025
Safe and effective vaccines have been instrumental in controlling and mitigating some of the most contagious and devastating diseases throughout history, ranging from smallpox, polio and diphtheria to measles, flu and coronavirus disease 2019 (COVID-19). Despite their proven success, vaccination rates often fall short of the World Health Organisation’s recommendations, facing persistent challenges. This review explores strategies to enhance vaccine uptake, with a particular focus on the UK context, by examining potential barriers, effective interventions and the vital role of various stakeholders. Boosting vaccine uptake requires a comprehensive approach that tackles issues such as vaccine hesitancy, improves accessibility, builds public trust, and utilises effective communication. By implementing targeted strategies, public bodies, scientists and healthcare professionals can work together to improve vaccination rates and safeguard communities against preventable diseases. Continuous evaluation and adaptation of these strategies are crucial to ensure their effectiveness and relevance in addressing the evolving challenges of vaccine uptake.
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | history |
| disease | MESH | smallpox |
| disease | MESH | polio |
| disease | MESH | diphtheria |
| disease | MESH | measles |
| pathway | KEGG | Measles |
| disease | MESH | coronavirus disease 2019 |
| drug | DRUGBANK | Spinosad |
| disease | IDO | role |