Telomere length and skin cancer risk: A systematic review and meta-analysis of melanoma, basal cell carcinoma and squamous cell carcinoma.

Publication date: Aug 01, 2025

Skin cancer is one of the most prevalent types of cancer worldwide, with its global incidence rising despite prevention efforts. Telomere length (TL) has emerged as a potential biomarker for cancer risk; however, its relationship with skin cancer risk remains incompletely understood. To explore the association between TL and the risk of melanoma, basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), a systematic review and meta-analysis was conducted. Longer TL was significantly associated with an increased risk in melanoma (pooled odds ratio: 0. 51; 95% confidence interval: 0. 38-0. 69; P

Concepts Keywords
Biomarker basal cell carcinoma
Carcinoma biomarker
Increased cancer
Oncol melanoma
skin cancer
squamous cell carcinoma
telomere biology
telomere length

Semantics

Type Source Name
disease MESH skin cancer
disease MESH melanoma
pathway KEGG Melanoma
disease MESH basal cell carcinoma
pathway KEGG Basal cell carcinoma
disease MESH squamous cell carcinoma
disease MESH cancer

Original Article

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