Publication date: Jun 15, 2025
Postural instability and gait difficulties (PIGD) are a significant cause of falls, and immobility in Parkinson’s disease (PD). Most gait assessments are based on assessing forward walking compared to retro walking. Retro walking is more difficult because of absence of visual cues, and more complex multisensory processing. Little is known about clinical PIGD motor features, mobility and body composition correlates of retro-walking compared to forward walking in PD. To examine the associations between retro and forward walking and PIGD in PD. 78 PD underwent clinical and body composition assessments. Multivariate logistic and linear forward stepwise regression analyses with were conducted to examine associations of retro- and forward walking times with PIGD motor features (falls, imbalance, FoG) and with clinical, body composition, and motor parameters. Logistic regression revealed that retro walking was associated with impaired balance (p = 0. 028), and falls (p = 0. 027) while forward walking was associated with FoG (p = 0. 047). Moreover, Mini-BESTest reactive postural control (p
| Concepts | Keywords |
|---|---|
| Bestest | Falls |
| Impaired | FoG |
| Parkinsonism | Forward walking |
| Walking | Imbalance |
| PIGD | |
| Retro walking |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Parkinson’s disease |
| disease | MESH | gait |
| drug | DRUGBANK | Isoxaflutole |