Publication date: Jun 27, 2025
Functional vs structural cortical deficit pattern biomarkers for major depressive disorder. Therefore, a more functional and ReHo based regional variability index (RVI) may be a useful novel biomarker for MDD. These pattern findings indicate that a functional, ReHo-based regional variability index may be an improved marker for MDD. Discovery and replication of cerebral blood flow differences in major depressive disorder. RCBF is closely linked with MDD, and ReHo measurements are connected to these blood flow changes. Data were sourced from different sets because there was no prior study which collected the same RCBF measurements the authors evaluated for both controls and MDD patients. Using fMRI data, investigators measured the amount of similarity in timing of resting-state BOLD signals in neighboring voxels of specific regions.
| Concepts | Keywords |
|---|---|
| Adobestockwith | Blood |
| Biomarkers | Cortical |
| Pathophysiology | Deficit |
| Depressive | |
| Disorder | |
| Flow | |
| Functional | |
| Homogeneity | |
| Major | |
| Mdd | |
| Rcbf | |
| Regional | |
| Reho | |
| Specific | |
| Structural |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | atrophy |
| disease | MESH | depression |
| disease | MESH | Major Depressive Disorder |