Publication date: Jun 26, 2025
Metastatic breast tumors are rare and often misdiagnosed as primary breast cancer. Herein, we present a case of breast metastasis from malignant melanoma. A 46-year-old woman presented to our department with a lump in her left breast. Examination revealed a relatively soft mass measuring 4 cm in diameter in the left breast. A needle biopsy was performed, and immunostaining for S-100, human melanoma black-45, CD56/neural cell adhesion molecule, and Melan-A confirmed a diagnosis of malignant melanoma. The metastasis was confined to the breast and was thus treated by surgery to excise the tumor. Malignant melanoma is a rare disease in the Japanese population and is associated with a poor prognosis because of the risk of early metastasis to multiple organs and lymph nodes. However, when complete resection of distant metastases is feasible, curative resection may be indicated. Herein, we report a case of breast metastasis from malignant melanoma and review previously published case reports on this rare condition.
| Concepts | Keywords |
|---|---|
| Biopsy | breast neoplasms |
| Cancer | melanoma |
| Complete | metastatic breast tumor |
| Japanese | prognosis |
| Misdiagnosed |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Melanoma |
| pathway | KEGG | Melanoma |
| disease | MESH | Metastasis |
| disease | MESH | breast tumors |
| pathway | KEGG | Breast cancer |
| disease | MESH | tumor |
| disease | MESH | rare disease |