Mapping Behavioral and Social Drivers of Influenza Vaccine Uptake in Older Adults: A Scoping Review.

Publication date: Jun 10, 2025

Background/Objectives: Influenza vaccination plays a crucial role in reducing morbidity and mortality among older adults; however, uptake remains suboptimal, particularly in the post-COVID-19 pandemic. In many settings, countries have not recovered their influenza vaccine coverage rates to the same level as pre-COVID. Therefore, this scoping review systematically identified the behavioral and social drivers (BeSD) influencing influenza vaccination among older adults using the BeSD framework. Methods: A systematic search across five databases included quantitative, qualitative, and mixed-methods studies involving individuals aged 60 years and older. Data were charted across four BeSD domains: thinking and feeling, social processes, motivation, and practical issues. Results: Thirty-nine studies from 24 countries were included. Key barriers encompassed safety concerns, misinformation, financial burdens, logistical challenges, and cultural and language barriers. While motivation was positively associated with vaccination intentions, the transition from intention to behavior remains underexplored, and practical issues have received comparatively limited research attention. Conclusions: These findings underscore the need for multifaceted, behaviorally informed interventions and greater inclusion of under-resourced settings to support equitable influenza vaccination strategies for healthy aging.

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Concepts Keywords
Databases barriers
Healthy facilitators
Influenza influenza vaccines
Misinformation older adults
Vaccination scoping review
vaccination

Semantics

Type Source Name
disease MESH Influenza
disease IDO role
disease MESH morbidity
disease MESH COVID-19 pandemic
disease MESH language barriers
disease IDO intervention
disease MESH lifestyles
drug DRUGBANK Factor IX Complex (Human)
disease IDO quality
drug DRUGBANK Methionine
disease IDO process
disease IDO country
drug DRUGBANK Methyl isocyanate
disease MESH education level
disease MESH chronic diseases
disease MESH obesity
disease IDO history
pathway REACTOME Influenza Infection
disease IDO susceptibility
disease MESH Marital status
disease MESH confusion
drug DRUGBANK Pentaerythritol tetranitrate
drug DRUGBANK Indoleacetic acid
disease MESH infection
disease MESH anxiety
drug DRUGBANK Serine
disease IDO replication
disease MESH Tetanus
disease MESH Herpes Zoster
drug DRUGBANK Guanosine
drug DRUGBANK Coenzyme A

Original Article

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