Publication date: Jun 07, 2025
Magnetic resonance diffusion tensor imaging (DTI) has been widely used in research and clinical practice for neurological disorders, and plays an increasingly important role in the research of ASD. This study aimed to explore the parametric characteristics of DTI in children with ASD, which further may serve to guide the diagnosis. Ninety children aged from 1 to 6 years old (male: female; 74:16) with ASD were selected to measure the parameters of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) of the genu of corpus callosum, splenium of corpus callosum, frontal lobe, superior temporal gyrus in DTI. A 32-channel cranial nerve coil of a GE Signa HDxt 3. 0T magnetic resonance system was used for the examination, and the FA and ADC maps were obtained by post-processing the DTI raw diffusion images with the Functool function software in the workstation. IBM SPSS 27. 00 statistical software was used for statistical analysis. In ASD children, FA values for the genu of corpus callosum, splenium of corpus callosum, and superior temporal gyrus were higher on the right than on the left, and ADC values for the genu of corpus callosum, splenium of corpus callosum, frontal lobe, and superior temporal gyrus were lower on the right than on the left (P
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| Concepts | Keywords |
|---|---|
| Autism | Autism spectrum disorder |
| Clinical | Corpus callosum |
| Hdxt | DTI |
| Ibm | Frontal lobe |
| Male | MRI |
| Neuroimaging | |
| Superior temporal gyrus |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | autism spectrum disorder |
| disease | MESH | neurological disorders |
| pathway | REACTOME | Reproduction |
| drug | DRUGBANK | Coenzyme M |