The Evolving Landscape of Functional Models of Autism Spectrum Disorder.

Publication date: Jun 16, 2025

Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 1-3% of the population globally. Owing to its multifactorial origin, complex genetics, and heterogeneity in clinical phenotypes, it is difficult to faithfully model ASD. In essence, ASD is an umbrella term for a group of individually rare disorders, each risk gene accounting for

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Concepts Keywords
Accounting Animals
Autism ASD
Genetics assembloid
Globally autism
Rare Autism Spectrum Disorder
CHD8
Disease Models, Animal
FMR1
Humans
iPSC
MECP2
Models, Biological
mouse model
organoid
Organoids
SHANK3

Semantics

Type Source Name
disease MESH Autism Spectrum Disorder
disease MESH neurodevelopmental disorder
drug DRUGBANK Coenzyme M
disease MESH autism
disease MESH Disease Models Animal

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