Clinical and histopathological characteristics of melanomas in Asians under age 40.

Publication date: Jul 01, 2025

Previous studies suggested racial difference between young melanomas of Caucasians and non-Caucasians. This study aimed to elucidate characteristics of melanomas in young Asians. We analyzed clinical and histologic characteristics of patients under age 40 diagnosed with cutaneous melanomas including in situs. Survival and subgroup analyses were conducted. Among the 45 patients investigated, the most common anatomical sites of melanomas were lower extremities (22/45, 45. 3%) and acral lentiginous type was the most common histological variety (18/45, 40%), of which 12 were subungual type. Lymph node involvement and nodular histologic type were significant prognostic factors. Age subgroup analysis revealed that clinical and histopathologic features of adolescents (15-21 years old [YO]) were distinct from those of young adults (22-39 YO), but similar to children (0-14 YO) who showed amelanotic nodules (p 

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Concepts Keywords
Adolescents Adolescent
Caucasians Adult
Histopathologic Age Factors
Lymph Asian People
Child
Child, Preschool
Ethnicity
Female
Humans
Infant
Infant, Newborn
Male
Melanoma
Melanoma
Pediatrics
Prognosis
Skin Neoplasms
Young Adult

Semantics

Type Source Name
disease MESH melanomas
drug DRUGBANK Methyprylon
pathway KEGG Melanoma
disease MESH Skin Neoplasms

Original Article

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