Evidence for fomite transmission of SARS-CoV-2 Omicron variant in a mouse model.

Publication date: Jun 01, 2025

Throughout the COVID-19 pandemic, the risk of fomite-based transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has not been systematically investigated. In this study, we employed the K18-hACE2 mouse infection model to experimentally assess the relative contribution of fomite transmission. Our findings indicate that while fomite transmission can occur in certain cases, the risk of fomite transmission in natural settings may be relatively low when appropriate hygiene practices are followed. These results may help optimize public health measures for more effective control of the COVID-19 pandemic.

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Concepts Keywords
Coronavirus Acute
Covid Based
K18 Cov
Low Covid
Pandemic Evidence
Fomite
Model
Omicron
Pandemic
Respiratory
Risk
Sars
Severe
Transmission
Variant

Semantics

Type Source Name
disease IDO fomite
disease MESH COVID-19 pandemic
disease MESH infection
drug DRUGBANK Coenzyme M
disease MESH severe acute respiratory syndrome
pathway REACTOME Reproduction
disease IDO pathogen
disease MESH Infectious Diseases
drug DRUGBANK Guanosine
disease MESH viral load
disease MESH weight gain
disease MESH weight loss
disease MESH pneumonia
disease MESH Respiratory Diseases
disease IDO infectivity
drug DRUGBANK Medical air
disease MESH recurrence

Original Article

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