Publication date: Jul 04, 2025
To use a literature review methodology to assess the efficacy of three distinct approaches: enucleation, radiotherapy or radiotherapy prior to enucleation, in reducing patient mortality. Computers were used to search databases such as PubMed, Web of Science, Embase, Cochrane Library, and CNKI, as well as the references of pertinent literature. Data were extracted from the included research literature according to the pre-defined data extraction table, encompassing study characteristics, sample size, interventions, outcome measures, etc. The Cochrane risk of bias evaluation instrument was employed to assess the excellence of encompassed researches, and the RevMan software was utilized for conducting the meta-analysis. 10 final articles were included, with 3 studies among them presenting the overall mortality rate at five-year follow-up. The homogeneity trial (P = 0. 02, I = 75%) showed remarkable heterogeneity, leading to the adoption of a random-effects model. The meta-analysis findings unveiled a distinction in the total mortality rate between the two groups (RR = 0. 98, 95%CI was 0. 81 ~ 1. 18, P
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | melanoma |
| pathway | KEGG | Melanoma |
| disease | MESH | Choroid Neoplasms |