Effectiveness of Cognitive Behavioral Therapy in Reducing Suicidal Ideation and Influential Factors in Patients With Major Depressive Disorder: A Systematic Review and Meta-Analysis.

Publication date: Jul 03, 2025

To evaluate the effectiveness of cognitive behavioral therapy (CBT) interventions in reducing suicidal ideation among patients with depression, and to identify factors that moderate treatment outcomes, a systematic review and meta-analysis was conducted searching seven major biomedical databases (CNKI, China Wanfang Database, Cochrane Library, PubMed, Web of Science, Embase, and Sinomed) from inception to November 8, 2023. Randomized controlled trials examining CBT interventions for suicidal ideation in depressed patients were included. Fourteen studies (1256 patients) met inclusion criteria. CBT demonstrated a moderate effect in reducing suicidal ideation compared to control conditions (Hedges’ g = -0. 47 (95% CI [-0. 73, -0. 22]), p 

Concepts Keywords
Biomedical cognitive behavioral therapy
China depression
Suicidal suicidal ideation
Therapy

Semantics

Type Source Name
disease MESH Suicidal Ideation
disease MESH Major Depressive Disorder
disease MESH depression
drug DRUGBANK Methionine
disease MESH Suicide

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