Publication date: Jul 05, 2025
Fecal transplantation has been shown to alter both the gut and mammary tumor microbiota, suggesting a link between the gut and mammary microbiota. Although further studies are needed, the hyperactivation of natural immune cells in the gut of HD patients may play a key role in gut dysbiosis. Metabolic disease research demonstrates: Diabetic patients decreased butyrate-producing bacteria directly correlate with insulin resistance, with microbiota modulation strategies partially reversing glucose metabolic abnormalities. Among these, the gut microbiota (GM) represents the functionally most sophisticated microbial consortium, whose metabolic potential exceeds the human genome by two orders of magnitude. Compared to healthy controls, the urinary microbiota composition in patients with genitourinary cancers exhibited significant differences. Within psychiatric disorders: Depressed patients show reduced short-chain fatty acid SCFAs levels closely associated with hypothalamic-pituitary-adrenal (HPA) axis hyperactivity. Gut microbiota dysbiosis manifests as increased abundance of Helicobacter spp.