Global prevalence of seasonal affective disorder by latitude: A systematic review and meta-analysis.

Publication date: Jul 02, 2025

Seasonal affective disorder (SAD) has been reported globally, yet no comprehensive meta-analysis has systematically examined the association between latitude and SAD prevalence. This study aimed to investigate the relationship between latitude and the prevalence of SAD, subsyndromal SAD (SSAD), and summer-type SAD. A systematic search was conducted in Medline, Embase, Web of Science, Scopus, and ScienceDirect on May 23, 2025. Eligible studies were cross-sectional and used the Seasonal Pattern Assessment Questionnaire (SPAQ) to diagnose SAD. Data were extracted on prevalence, latitude, age, sex, region, income level, and KcF6ppen climate zones. Pooled prevalence rates were calculated using a random-effects model. Meta-regression and subgroup analyses were performed to assess the influence of latitude and other moderators. Twenty-four studies with 32,866 participants were included. The pooled prevalence of SAD was 5. 70 % (95 % CI: 5. 07-6. 33), SSAD was 10. 63 % (95 % CI: 9. 24-12. 02), and summer-type SAD was 1. 47 % (95 % CI: 1. 32-1. 61). Meta-regression revealed a significant positive association between latitude and both SAD (β = 0. 14, p 

Concepts Keywords
Latitude Latitude
Medline Meta-analysis
Sciencedirect Prevalence
Spaq Seasonal affective disorder
Summer Systematic review

Semantics

Type Source Name
disease MESH seasonal affective disorder

Original Article

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